physiology
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A day of low fluid intake 0 seconds

Follow how the body defends its water over a day when fluid intake stays low.

Representative model
Change event
Representative whole-body physiology diagramActive organs become brighter as the timeline moves.
The kidneys hold on to water

Vasopressin reaches the kidney, where the collecting duct becomes more permeable to water, so more water returns to the blood and less leaves as urine.

Interactive 3D is loading into this same frame contract.

00:00:00
  • Low intake begins · 00:00:00
  • A small deficit builds · 04:00:00
  • Water conservation ramps up · 08:00:00
  • Thirst and blood concentration rise · 13:00:00
  • Urine is highly concentrated · 18:00:00
  • One day on · 24:00:00
Happening now

Fluid intake is low while the usual routes of water loss carry on.

Explore the mechanism Water keeps leaving

Water leaves the body through the kidneys, the skin, the breath and the gut, even when little is coming in.

Evidence for this step

Water typically leaves the body without pause through the kidneys, skin, breathing and the gut, so a day with little fluid intake usually produces a net body-water deficit. moderate · View sources

Time: 0 seconds. Milestone: Low intake begins. Active anatomy: Whole-body context, Kidneys. Metrics: Body-water deficit (share of starting body mass): typically between 0 and 0 of 1; Blood concentration (plasma osmolality): steady; Water-conserving hormone signal (vasopressin): steady
  • Whole-body context: 10%
  • Kidneys: 30%
  • Nephron and collecting duct: 25%
  • Bloodstream: 20%
  • Endocrine signalling: 15%